Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ME2 | P23368 | 1/20 | 0.35 |
| ▸ | ME1 | P48163 | 1/20 | 0.35 |
| ▸ | ME3 | Q16798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955395 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2HRH3ALDH1A1CHRM1KCNH2 | |
| SCHEMBL7666266 | 0.82 | KMT2A (0.51) | SMN1; SMN2ALDH1A1KMT2AUSP2MAPK1 | |
| SCHEMBL9650536 | 0.80 | CYP2B6 (0.46) | SMN1; SMN2ALDH1A1CHRM1KCNH2CHRM3 | |
| SCHEMBL818967 | 0.79 | CHRM1 (0.47) | SMN1; SMN2ALDH1A1CHRM1CHRM3CHRM4 | |
| SCHEMBL22106794 | 0.78 | MEN1 (0.42) | ALDH1A1CHRM3KMT2AMEN1LMNA | |
| SCHEMBL17523153 | 0.78 | BLM (0.59) | ALDH1A1KMT2AMEN1TSHRLMNA | |
| SCHEMBL17523154 | 0.77 | MGLL (0.56) | SMN1; SMN2ALDH1A1KMT2AMEN1USP2 | |
| SCHEMBL2867370 | 0.76 | GPR119 (0.53) | SMN1; SMN2ALDH1A1CHRM1CHRM3CHRM4 | |
| SCHEMBL27906266 | 0.76 | TSHR (0.57) | SMN1; SMN2ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL20324400 | 0.73 | LMNA (0.42) | SMN1; SMN2ALDH1A1CHRM4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355640-B1 | TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| US-5773530-A | USEFUL AS PSYCHOSTIMULANTS, ANTIHYPERTENSIVE AGENTS AND REMEDIES FOR RENAL FAILURE, DIURETICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |