Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170239 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTKEAP1FFAR2SERPINE1 | |
| SCHEMBL1653895 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTKEAP1SERPINE1ALDH1A1 | |
| SCHEMBL2035385 | 0.72 | NOTUM (0.55) | SMN1; SMN2MAPTKEAP1ALDH1A1MEN1 | |
| SCHEMBL31240267 | 0.72 | NOTUM (0.55) | SMN1; SMN2MAPTKEAP1ALDH1A1MEN1 | |
| SCHEMBL7981185 | 0.71 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTKEAP1SERPINE1ALDH1A1 | |
| SCHEMBL7978483 | 0.71 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTKEAP1SERPINE1ALDH1A1 | |
| SCHEMBL13554691 | 0.65 | MAPT (0.71) | SMN1; SMN2MAPTSERPINE1ALDH1A1MEN1 | |
| SCHEMBL3727147 | 0.64 | MMP8 (0.58) | SMN1; SMN2MAPTALDH1A1HTTLMNA | |
| SCHEMBL2934025 | 0.64 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTKEAP1SERPINE1ALDH1A1 | |
| SCHEMBL11445686 | 0.64 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369057-B1 | VIRICIDES, IN PARTICULAR AGAINST RETROVIRUSES, HUMAN IMMUNODEFICIENCY VIRUS (HIV) | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |