Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.61 |
| ▸ | HTR7 | P34969 | 6/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7662224 | 0.99 | HTR1A (0.63) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| Hydrochloric Acid SCHEMBL7672833 | 0.99 | HTR1A (0.63) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| Hydrochloric Acid SCHEMBL7668625 | 0.91 | HTR1A (0.58) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| SCHEMBL7458906 | 0.91 | HTR1A (0.73) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| SCHEMBL7691096 | 0.90 | ADRA1D (0.52) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| Hydrochloric Acid SCHEMBL7673322 | 0.89 | HTR1A (0.53) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| Hydrochloric Acid SCHEMBL7662582 | 0.89 | HTR1A (0.53) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| SCHEMBL7467800 | 0.89 | HTR1A (0.75) | HTR1ASLC6A4HTR7KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL7670760 | 0.87 | DRD2 (0.56) | HTR1AADRA1DSLC6A4HTR7KCNH2 | |
| SCHEMBL7664024 | 0.85 | HTR1A (0.54) | HTR1ASLC6A4HTR7KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342498-B1 | SEROTONIN REUPTAKE INHIBITORS FOR BRAIN DISORDERS | ELI LILLY AND COMPANY | 2002-01-29 | — | — | US | claimed |
| WO-2020183011-A1 | HTR1D INHIBITORS AND USES THEREOF IN THE TREATMENT OF CANCER | INSTITUT CURIE (FR) | 2020-09-17 | — | — | WO | disclosed |