SCHEMBL7667201

SCHEMBL7667201

COc1nn(C)c(=O)n1Cc1cc(Br)ccc1C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
P2RX7 Q99572 1/20 0.36
POLB P06746 1/20 0.35
MC4R P32245 6/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
PTGER1 P34995 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7660068 0.86 TLR7 (0.42) TP53MAPTP2RX7POLBKDM4E
SCHEMBL7667892 0.86 POLB (0.38) TP53MAPTLMNAP2RX7POLB
SCHEMBL7674200 0.84 TP53 (0.40) TP53MAPTLMNAP2RX7POLB
SCHEMBL7669141 0.82 TP53 (0.44) TP53MAPTLMNAKDM4ESMN1; SMN2
SCHEMBL7671615 0.81 HPGD (0.41) TP53MAPTLMNAP2RX7KDM4E
SCHEMBL7671400 0.81 TP53 (0.41) TP53MAPTLMNAPOLBSMN1; SMN2
SCHEMBL7669474 0.80 ROCK2 (0.40) TP53MAPTLMNAP2RX7SMN1; SMN2
SCHEMBL7689852 0.79 TP53 (0.37) TP53MAPTLMNAP2RX7
SCHEMBL7672496 0.79 TP53 (0.41) TP53MAPTLMNAKDM4E
SCHEMBL7674096 0.79 KCNH2 (0.38) TP53MAPTLMNAPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12439917-B2 Method for controlling phakopsora pachyrhizi having resistance against QoI fungicide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2025-10-14 US disclosed
US-20230127143-A1 METHOD FOR CONTROLLING PHAKOPSORA PACHYRHIZI HAVING RESISTANCE AGAINST QoI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
WO-2021153782-A1 METHOD FOR CONTROLLING PHAKOPSORA PACHYRHIZI HAVING RESISTANCE AGAINST QoI FUNGICIDE 住友化学株式会社 2021-08-05 WO disclosed
US-6489487-B1 AGRICULTURAL OR HORTICULTURAL FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-03 US disclosed
EP-1103548-A1 TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127143-A1 METHOD FOR CONTROLLING PHAKOPSORA PACHYRHIZI HAVING RESISTANCE AGAINST QoI FUNGICIDE CYC1, COX5B, SQOR TP53 2227/4885MAPT 1164/4885LMNA 2649/4885
US-12439917-B2 Method for controlling phakopsora pachyrhizi having resistance against QoI fungicide CYC1, COX5B, SQOR TP53 2227/4885MAPT 1164/4885LMNA 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.