Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 11/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210797 | 0.82 | TSPO (0.57) | GRIN1GRIN2BTSPO | |
| SCHEMBL7217070 | 0.78 | TSPO (0.53) | GRIN1GRIN2BTSPOTSHRPOLB | |
| SCHEMBL7216925 | 0.76 | TSPO (0.56) | GRIN1GRIN2BTSPOTSHRSMN1; SMN2 | |
| SCHEMBL7212081 | 0.76 | LMNA (0.60) | TSPOTSHR | |
| SCHEMBL7215601 | 0.76 | TSPO (0.58) | GRIN1GRIN2BTSPO | |
| SCHEMBL6482823 | 0.74 | TSPO (0.61) | GRIN1GRIN2BTSPO | |
| SCHEMBL7215395 | 0.74 | TSPO (0.67) | GRIN1GRIN2BTSPO | |
| Hydrochloric Acid SCHEMBL7212073 | 0.73 | TSPO (0.60) | GRIN1GRIN2BTSPO | |
| SCHEMBL7217013 | 0.73 | TSPO (0.58) | GRIN1GRIN2BTSPO | |
| SCHEMBL7667254 | 0.72 | ALDH1A1 (0.38) | TSPOTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372740-B1 | NERVOUS SYSTEM DISORDERS, ANTIEPILEPTIC AGENTS AND ANTIDEPRESSANTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-1036794-A1 | 2-ARYL-8-OXODIHYDROPURINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME, AND INTERMEDIATES THEREOF | Dainippon Pharmaceutical Co., Ltd. (JP) | 2000-09-20 | — | — | EP | disclosed |