Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667245 | 0.72 | GRIN1 (0.49) | TSHRTSPO | |
| SCHEMBL10369069 | 0.66 | ADORA2B (0.52) | ALDH1A1MEN1GAAKMT2ATSHR | |
| SCHEMBL7217031 | 0.65 | TSPO (0.48) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL7210797 | 0.64 | TSPO (0.57) | ALDH1A1TSPOHSD17B10GRM2 | |
| SCHEMBL10007507 | 0.63 | HPGD (0.45) | MEN1KMT2ATSHRMAPK1TSPO | |
| SCHEMBL10007263 | 0.63 | HPGD (0.47) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL10006720 | 0.63 | HPGD (0.49) | ALDH1A1TSHRL3MBTL1MAPK1TSPO | |
| SCHEMBL10007314 | 0.61 | KCNH2 (0.42) | TSPO | |
| SCHEMBL7217070 | 0.61 | TSPO (0.53) | TSHRL3MBTL1TSPOGRM2 | |
| SCHEMBL10007254 | 0.61 | L3MBTL1 (0.44) | ALDH1A1MEN1GAAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372740-B1 | NERVOUS SYSTEM DISORDERS, ANTIEPILEPTIC AGENTS AND ANTIDEPRESSANTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2002-04-16 | — | — | US | disclosed |
| EP-1036794-A1 | 2-ARYL-8-OXODIHYDROPURINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, MEDICINAL COMPOSITIONS CONTAINING THE SAME, AND INTERMEDIATES THEREOF | Dainippon Pharmaceutical Co., Ltd. (JP) | 2000-09-20 | — | — | EP | disclosed |