SCHEMBL7667385

SCHEMBL7667385

CNc1ccccc1C(=O)NC(C)CC(=O)OC

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.51
POLB P06746 2/20 0.51
ATM Q13315 2/20 0.51
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ALDH1A1 P00352 5/20 0.44
ADRA1A P35348 2/20 0.44
ADRA1D P25100 1/20 0.43
ADRA1B P35368 1/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.42
CRBN Q96SW2 1/20 0.41
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7673771 0.85 KMT2A (0.49) KDM4EPOLBATMMEN1KMT2A
SCHEMBL7660852 0.81 ALDH1A1 (0.44) KDM4EPOLBATMMEN1KMT2A
SCHEMBL13761443 0.81 KDM4E (0.59) KDM4EPOLBATMMEN1KMT2A
SCHEMBL7321127 0.81 ALDH1A1 (0.36) KDM4EPOLBATMMEN1KMT2A
SCHEMBL1185757 0.77 RAB9A (0.58) POLBMEN1KMT2AHPGDALDH1A1
SCHEMBL24344002 0.71 GRN (0.51)
SCHEMBL20366937 0.71 THRB (0.51) POLBMEN1KMT2AHPGDALDH1A1
SCHEMBL960781 0.71 KDM4E (0.58) KDM4EPOLBATMMEN1KMT2A
SCHEMBL14947473 0.71 ADRA1D (0.59) KDM4EPOLBATMMEN1KMT2A
SCHEMBL17483031 0.71 KDM4E (0.58) KDM4EPOLBATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348614-B1 PROTECTING CROPS AGAINST PLANT DISEASES AGROGENE LTD. (IL) 2002-02-19 US claimed
EP-0948481-A1 AMINOBUTYRIC ACID FUNGICIDES Agrogene Ltd. (IL) 1999-10-13 EP claimed
WO-1998029387-A1 AMINOBUTYRIC ACID FUNGICIDES AGROGENE LTD. (IL) 1998-07-09 WO claimed
US-6348614-B1 PROTECTING CROPS AGAINST PLANT DISEASES AGROGENE LTD. (IL) 2002-02-19 US disclosed
EP-0948481-A1 AMINOBUTYRIC ACID FUNGICIDES Agrogene Ltd. (IL) 1999-10-13 EP disclosed
WO-1998029387-A1 AMINOBUTYRIC ACID FUNGICIDES AGROGENE LTD. (IL) 1998-07-09 WO disclosed