SCHEMBL766761

SCHEMBL766761

O=C(O)Oc1ccccc1C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.70
ALDH1A1 P00352 9/20 0.70
HSD17B10 Q99714 7/20 0.70
HPGD P15428 6/20 0.70
HMGB1 P09429 2/20 0.70
NAPRT Q6XQN6 2/20 0.70
ESR1 P03372 1/20 0.70
ITGB3 P05106 1/20 0.70
ITGA2B P08514 1/20 0.70
TSHR P16473 1/20 0.70
GGT1 P19440 1/20 0.70
PTGS1 P23219 1/20 0.70
PTGS2 P35354 1/20 0.70
BLM P54132 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
MAPT P10636 1/20 0.68
LMNA P02545 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2C9 P11712 1/20 0.61
USP2 O75604 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1721235 0.86 KDM4E (0.78) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL11208120 0.84 KDM4E (0.79) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL6257888 0.84 KDM4E (0.52) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL143632 0.83 KDM4E (0.46) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL1810676 0.83 KDM4E (0.66) KDM4EALDH1A1HSD17B10HPGDHMGB1
Aspirin SCHEMBL10456693 0.83 KDM4E (1.00) KDM4EALDH1A1HSD17B10HPGDHMGB1
Aspirin SCHEMBL1353 0.83 KDM4E (1.00) KDM4EALDH1A1HSD17B10HPGDHMGB1
Aspirin SCHEMBL7580 0.83 KDM4E (1.00) KDM4EALDH1A1HSD17B10HPGDHMGB1
SCHEMBL13189200 0.83 KDM4E (0.66) KDM4EALDH1A1HSD17B10HPGDHMGB1
Aspirin SCHEMBL1331740 0.83 KDM4E (1.00) KDM4EALDH1A1HSD17B10HPGDHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299000-B2 Slow release lubricant additives gel THE LUBRIZOL CORPORATION (US) 2012-10-30 US claimed
US-20120067798-A1 Slow Release Lubricant Additives Gel THE LUBRIZOL CORPORATION (US) 2012-03-22 US claimed
US-20100317553-A1 Slow Release Lubricant Additives Gel BURRINGTON JAMES D 2010-12-16 US claimed
US-7799745-B2 Slow release lubricant additives gel THE LUBRIZOL CORPORATION (US) 2010-09-21 US claimed
US-20080257803-A1 Slow Release Lubricant Additives Gel THE LUBRIZOL CORPORATION (US) 2008-10-23 US claimed
US-7417012-B2 Slow release lubricant additives gel THE LUBRIZOL CORPORATION (US) 2008-08-26 US claimed
EP-1799747-A1 METHOD FOR INCORPORATING ALKYL ESTER ENDGROUPS TO IMPROVE THE RELEASE PROPERTIES OF MELT POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2007-06-27 EP claimed
WO-2006031668-A1 METHOD FOR INCORPORATING ALKYL ESTER ENDGROUPS TO IMPROVE THE RELEASE PROPERTIES OF MELT POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2006-03-23 WO claimed
EP-1622996-A1 SLOW RELEASE LUBRICANT ADDITIVES GEL THE LUBRIZOL CORPORATION (US) 2006-02-08 EP claimed
US-20050085399-A1 Slow release lubricant additives gel BURRINGTON JAMES D (US) 2005-04-21 US claimed
EP-0985726-B1 Production of high BN alkaline earth metal single-aromatic ring hydrocarbyl salicylate-carboxylate CHEVRON CHEM SA (FR) 2004-11-17 EP claimed
WO-2004007653-A9 SLOW RELEASE LUBRICANT ADDITIVES GEL LUBRIZOL CORP (US) 2004-06-10 WO claimed
WO-2004007653-A2 SLOW RELEASE LUBRICANT ADDITIVES GEL THE LUBRIZOL CORPORATION (US) 2004-01-22 WO claimed
US-20040014614-A1 Slow release lubricant additives gel LUBRIZOL CORPORATION, THE 2004-01-22 US claimed
US-6348438-B1 OVERBASING BY CONTACT WITH CARBON DIOXIDE, SOLVENT, METAL HYDROXIDE, AND ALKYL POLYHYDRIC ALCHOL; COMPATIBILITY WITH SULFONATES; HEAT AND OXIDATION RESISTANCE OF LUBRICANTS CHEVRON ORONITE S.A. (FR) 2002-02-19 US claimed
EP-0985726-A1 Production of high BN alkaline earth metal single-aromatic ring hydrocarbyl salicylate-carboxylate Chevron Chemical S.A. (FR) 2000-03-15 EP claimed
JP-5001140-A None JP disclosed
EP-2540697-B1 METHOD FOR PRODUCING DIARYL CARBONATE ASAHI CHEMICAL IND (JP) 2022-04-20 EP disclosed
EP-0228298-A2 Stable soluble 1,2-diamino-cyclohexane platinum complexes ANDRULIS RESEARCH CORPORATION (US) 1987-07-08 EP disclosed
US-3806521-A SALICYLATE CARBONATE COMPOUNDS LIGGETT GROUP INC. 1974-04-23 US disclosed