Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495608 | 0.78 | ENPP1 (0.57) | ENPP1ENPP3FLT3NPC1RAB9A | |
| SCHEMBL5188682 | 0.76 | ALDH1A1 (0.43) | ENPP1ENPP3NPC1RAB9AMEN1 | |
| SCHEMBL4724144 | 0.74 | ALDH1A1 (0.41) | FLT3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22373678 | 0.73 | CYP1A1 (0.49) | ENPP1ENPP3FLT3NPC1RAB9A | |
| Formaldehyde SCHEMBL23148501 | 0.73 | CA12 (0.53) | ENPP1ENPP3FLT3CA12CA1 | |
| SCHEMBL18731830 | 0.71 | L3MBTL1 (0.51) | ENPP1ENPP3FLT3NPC1RAB9A | |
| SCHEMBL4724855 | 0.70 | ENPP1 (0.44) | ENPP1MEN1KMT2AMAPTPOLB | |
| SCHEMBL22978418 | 0.70 | ENPP1 (0.46) | ENPP1ENPP3FLT3NPC1RAB9A | |
| SCHEMBL15715826 | 0.69 | HPGD (0.52) | ENPP1ENPP3NPC1RAB9AMEN1 | |
| SCHEMBL29269085 | 0.69 | DHFR (0.47) | ENPP1ENPP3FLT3RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441174-B1 | REACTING PERYLENE-3,4,9,10-TETRACARBOXIMIDE OR DERIVATIVES WITH FORMALDEHYDE TO FORM BIS(HYDROXYMETHYL)PERYLENE-3,4,9,10-TETRACARBOXIMIDE, WHICH FURTHER REACTS WITH A PRECURSOR OF ORGANIC REDICALS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-08-27 | — | — | US | disclosed |