Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671417 | 0.82 | GAA (0.39) | VKORC1ALOX5ALDH1A1KDM4EGAA | |
| SCHEMBL7666716 | 0.80 | SMN1; SMN2 (0.39) | VKORC1ALOX5ALDH1A1KDM4EGAA | |
| SCHEMBL7668581 | 0.80 | GSK3B (0.37) | VKORC1ALOX5ALDH1A1TP53POLB | |
| SCHEMBL7662117 | 0.79 | PTGDR2 (0.36) | ALDH1A1KDM4EGAASMN1; SMN2LMNA | |
| SCHEMBL7663982 | 0.78 | TP53 (0.39) | VKORC1KDM4EGAATP53LMNA | |
| SCHEMBL7687283 | 0.77 | RIPK1 (0.40) | ALOX5ALDH1A1TP53PKMCYP1B1 | |
| SCHEMBL7666493 | 0.74 | GABRA1 (0.40) | VKORC1ALOX5KDM4ELMNAPLA2G7 | |
| SCHEMBL7670688 | 0.74 | RIPK1 (0.38) | ALDH1A1GAAPKM | |
| SCHEMBL7673275 | 0.73 | PKM (0.36) | ALDH1A1PKM | |
| SCHEMBL7666654 | 0.73 | PKM (0.36) | ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |