SCHEMBL7669389

SCHEMBL7669389

CCCN(SCc1cccnc1)C(=O)NC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.40
CCNE2 O96020 1/20 0.40
CCNE1 P24864 1/20 0.40
CDK2 P24941 1/20 0.40
MAPT P10636 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
FAAH O00519 1/20 0.40
RIPK1 Q13546 1/20 0.40
RECQL P46063 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
CHRNA7 P36544 1/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7669795 0.90 CHRNB2 (0.44) PKMKMT2ACCNE2CCNE1CDK2
SCHEMBL7662010 0.86 TDP1 (0.43) PKMKMT2ATSHRCCNE2CCNE1
SCHEMBL7667027 0.74 KMT2A (0.49) PKMKMT2ATSHRCCNE2CCNE1
SCHEMBL8406145 0.73 PTGES (0.47) PKMKMT2ACCNE2CCNE1CDK2
SCHEMBL7670524 0.72 CHRNA7 (0.49) PKMKMT2ANAPRTRIPK1RECQL
SCHEMBL2187781 0.72 TDP1 (0.52) KMT2AMAPTFAAHRIPK1TDP1
SCHEMBL10408792 0.67 NAPRT (0.50) PKMKMT2ACCNE2CCNE1CDK2
SCHEMBL10673299 0.67 SMN1; SMN2 (0.48) KMT2ATSHRCCNE2CCNE1CDK2
SCHEMBL7669395 0.67 KMT2A (0.54) KMT2AMAPTL3MBTL1CHRNB2CHRNA4
SCHEMBL9388351 0.67 CYP3A4 (0.55) PKMKMT2ACCNE2CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed