Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667027 | 0.83 | KMT2A (0.49) | PKMKMT2ALMNACCNE2CCNE1 | |
| SCHEMBL24568366 | 0.80 | LMNA (0.60) | PTGESPKMKMT2ALMNAAKR1C3 | |
| SCHEMBL7670524 | 0.73 | CHRNA7 (0.49) | PKMKMT2ACHRNB2CHRNA4TBXAS1 | |
| SCHEMBL24011470 | 0.73 | CYP1A2 (0.64) | PKMKMT2ALMNATBXAS1CYP1A2 | |
| SCHEMBL7669389 | 0.73 | PKM (0.41) | PKMKMT2ACCNE2CCNE1CDK2 | |
| SCHEMBL7669795 | 0.72 | CHRNB2 (0.44) | PKMKMT2ALMNACCNE2CCNE1 | |
| SCHEMBL21890782 | 0.71 | CYP1A2 (0.57) | LMNATBXAS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19000037 | 0.69 | PKM (0.48) | PKMKMT2ALMNATBXAS1CYP1A2 | |
| SCHEMBL7670730 | 0.69 | SMN1; SMN2 (0.58) | PTGESKMT2ALMNACHRNB2CHRNA4 | |
| SCHEMBL7305512 | 0.68 | LMNA (0.58) | PKMKMT2ALMNACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |