SCHEMBL7662010

SCHEMBL7662010

CNC(=O)N(CCOC)SCc1cccnc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
LTA4H P09960 1/20 0.41
GAA P10253 1/20 0.41
TSHR P16473 2/20 0.41
RECQL P46063 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ALDH1A1 P00352 3/20 0.39
MMP13 P45452 1/20 0.39
USP2 O75604 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PKM P14618 1/20 0.39
KMT2A Q03164 1/20 0.39
KCNA5 P22460 1/20 0.39
GFER P55789 3/20 0.39
CCNE2 O96020 1/20 0.38
CCNE1 P24864 1/20 0.38
CDK2 P24941 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7669389 0.86 PKM (0.41) TDP1TSHRRECQLSMN1; SMN2ALDH1A1
SCHEMBL7669795 0.84 CHRNB2 (0.44) RECQLSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL7670524 0.69 CHRNA7 (0.49) TDP1RECQLL3MBTL1PKMKMT2A
SCHEMBL14276916 0.69 SMN1; SMN2 (0.51) SMN1; SMN2ALDH1A1PKMKMT2AKCNA5
SCHEMBL7662014 0.69 KDM4E (0.55) SMN1; SMN2ALDH1A1KMT2ALMNAMAPT
SCHEMBL7667027 0.69 KMT2A (0.49) GAATSHRRECQLSMN1; SMN2ALDH1A1
SCHEMBL8406145 0.68 PTGES (0.47) RECQLL3MBTL1PKMKMT2ACCNE2
SCHEMBL8065479 0.67 SMN1; SMN2 (0.48) LTA4HSMN1; SMN2ALDH1A1PKMKMT2A
SCHEMBL8066367 0.66 RIPK1 (0.53) TDP1LTA4HGAATSHRSMN1; SMN2
SCHEMBL23135441 0.65 MAPT (0.69) TDP1GAARECQLSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed