SCHEMBL766945

SCHEMBL766945

C=C(CCc1cccc2cc3ccccc3cc12)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 9/20 0.44
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 1/20 0.41
MTNR1B P49286 5/20 0.39
GPR84 Q9NQS5 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NQO2 P16083 1/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP1A2 P05177 1/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FFAR1 O14842 1/20 0.37
AKR1B1 P15121 1/20 0.37
PTGER1 P34995 1/20 0.37
PTGER4 P35408 1/20 0.37
PTGER3 P43115 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1989843 0.86 TDP1 (0.54) MTNR1AKDM4EGPR84TDP1CYP1A2
SCHEMBL2243225 0.84 TDP1 (0.49) MTNR1AKDM4EALDH1A1GAAMTNR1B
SCHEMBL5593879 0.84 PTGER1 (0.51) MTNR1AKDM4EALDH1A1GAATDP1
SCHEMBL30532048 0.83 PTGER1 (0.50) MTNR1AKDM4EALDH1A1GAATDP1
SCHEMBL1568310 0.81 MTNR1A (0.48) MTNR1AKDM4EALDH1A1GAAMTNR1B
SCHEMBL3178981 0.80 CYP1A2 (0.45) KDM4EALDH1A1TDP1MEN1KMT2A
SCHEMBL1989802 0.80 KDM4E (0.46) KDM4EALDH1A1GAATDP1MEN1
SCHEMBL31043020 0.80 IAPP (0.51) MTNR1AKDM4EALDH1A1GAAMTNR1B
SCHEMBL29113112 0.78 MEN1 (0.60) MTNR1AKDM4EALDH1A1GAAMTNR1B
SCHEMBL7560914 0.77 TDP1 (0.51) MTNR1AKDM4ETDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11392037-B2 Resist underlayer film forming composition containing silicone having cyclic amino group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2022-07-19 US disclosed
EP-3670543-A2 POLYMER PRODUCTION METHOD Nissan Chemical Corporation (JP) 2020-06-24 EP disclosed
US-10174255-B2 Thermosetting composition with photo-alignment property, alignment layer, substrate with alignment layer, retardation plate, and device DAI NIPPON PRINTING CO., LTD. (JP) 2019-01-08 US disclosed
US-10017697-B2 Thermosetting composition with photo-alignment property, alignment layer, substrate with alignment layer, retardation plate, and device DAI NIPPON PRINTING CO., LTD. (JP) 2018-07-10 US disclosed
US-10017696-B2 Thermosetting composition with photo-alignment property, alignment layer, substrate with alignment layer, retardation plate, and device DAI NIPPON PRINTING CO., LTD. (JP) 2018-07-10 US disclosed
US-9760006-B2 Silicon-containing resist underlayer film forming composition having urea group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-09-12 US disclosed
US-20160355735-A1 THERMOSETTING COMPOSITION WITH PHOTO-ALIGNMENT PROPERTY, ALIGNMENT LAYER, SUBSTRATE WITH ALIGNMENT LAYER, RETARDATION PLATE, AND DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2016-12-08 US disclosed
US-20160348004-A1 THERMOSETTING COMPOSITION WITH PHOTO-ALIGNMENT PROPERTY, ALIGNMENT LAYER, SUBSTRATE WITH ALIGNMENT LAYER, RETARDATION PLATE, AND DEVICE DAI NIPPON PRINTING CO., LTD. (JP) 2016-12-01 US disclosed
US-9217921-B2 Resist underlayer film forming composition containing silicon having sulfide bond NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-22 US disclosed
US-20150322219-A1 BOTTOM LAYER FILM-FORMATION COMPOSITION OF SELF-ORGANIZING FILM CONTAINING POLYCYCLIC ORGANIC VINYL COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-11-12 US disclosed
US-20110143149-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICONE HAVING ONIUM GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-06-16 US disclosed
US-20100330505-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICONE HAVING CYCLIC AMINO GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-30 US disclosed
US-20100304305-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING POLYMER HAVING NITROGEN-CONTAINING SILYL GROUP NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-02 US disclosed
US-7838606-B2 Production process of copolymer for semiconductor lithography MARUZEN PETROCHEMICAL CO., LTD (JP) 2010-11-23 US disclosed
US-20100291487-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION HAVING UREA GROUP NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2010-11-18 US disclosed
EP-2249204-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING CYCLIC AMINO GROUP Nissan Chemical Industries, Ltd. (JP) 2010-11-10 EP disclosed
EP-2196854-A1 COMPOSITION CONTAINING POLYMER HAVING NITROGENOUS SILYL GROUP FOR FORMING RESIST UNDERLAYER FILM Nissan Chemical Industries, Ltd. (JP) 2010-06-16 EP disclosed
US-7663301-B2 for use as robust red organic phosphors GENERAL ELECTRIC COMPANY (US) 2010-02-16 US disclosed
WO-2006076247-A2 PHOSPHORESCENT FLUORENE, ANTHRACENE AND/OR THIOPHENE SUBSTITUTED METALLO- PORPHYRINS AND RELATED COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2006-07-20 WO disclosed
US-20060152149-A1 Porphyrin compositions GENERAL ELECTRIC COMPANY (US) 2006-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110143149-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICONE HAVING ONIUM GROUP SRR, KDM2B, MSR1 MTNR1A 4156/4885KDM4E 46/4885ALDH1A1 3585/4885
US-20060152149-A1 Porphyrin compositions ACP1, MMS19, MVD MTNR1A 2767/4885KDM4E 2546/4885ALDH1A1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.