Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671224 | 0.90 | PRSS1 (0.35) | F2F10PRSS1NAMPTHSD11B1 | |
| SCHEMBL6563261 | 0.88 | HSD11B1 (0.38) | F2F10PRSS1NAMPTHSD11B1 | |
| SCHEMBL6565512 | 0.86 | GAA (0.40) | F2F10PRSS1NAMPTHSD11B1 | |
| SCHEMBL6561970 | 0.81 | GAA (0.49) | F2NAMPTHSD11B1GAAHPGD | |
| SCHEMBL6561930 | 0.81 | MEN1 (0.39) | NAMPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL6561843 | 0.79 | GAA (0.31) | NAMPTHSD11B1ITGB3ITGA2BGAA | |
| SCHEMBL6565424 | 0.78 | ITGB3 (0.42) | F2PRSS1HSD11B1ITGB3ITGA2B | |
| SCHEMBL6564299 | 0.77 | GAA (0.36) | F2F10PRSS1NAMPTHSD11B1 | |
| SCHEMBL6563410 | 0.77 | GAA (0.40) | F2F10PRSS1NAMPTHSD11B1 | |
| SCHEMBL6564957 | 0.77 | F2 (0.38) | F2F10PRSS1HSD11B1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |