SCHEMBL7670090

SCHEMBL7670090

CCCCN(C(=S)NC)c1ccc(Cl)nc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.34
EGFR P00533 1/20 0.34
ERBB2 P04626 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
FAAH O00519 1/20 0.33
DGAT1 O75907 1/20 0.33
PTGES O14684 1/20 0.32
FFAR2 O15552 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7668563 0.92 MEN1 (0.39) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7667961 0.86 ALDH1A1 (0.43) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7664945 0.84 ROCK2 (0.44) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7669449 0.76 MAPT (0.34) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7663895 0.75 LMNA (0.51) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7660392 0.75 ALDH1A1 (0.44) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7671934 0.74 MEN1 (0.36) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7671929 0.74 MEN1 (0.36) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7671994 0.73 L3MBTL1 (0.42) LMNAMEN1KMT2AALDH1A1MAPT
SCHEMBL7667371 0.71 MEN1 (0.49) LMNAMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed