Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.66 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661857 | 1.00 | OPRM1 (0.66) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL7670083 | 1.00 | OPRM1 (0.66) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL7661852 | 1.00 | OPRM1 (0.66) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL7661867 | 1.00 | OPRM1 (0.66) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL7666333 | 0.83 | OPRM1 (0.46) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL11290168 | 0.80 | DRD2 (0.50) | OPRM1OPRD1OPRK1DRD2DRD3 | |
| SCHEMBL7212881 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1 | |
| SCHEMBL7212882 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1 | |
| SCHEMBL7655297 | 0.79 | OPRM1 (1.00) | OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL11291604 | 0.79 | DRD2 (0.49) | OPRM1OPRD1OPRK1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498196-B1 | THIO-AMINOTETRALINS; ANALGESICS; OPIOID RECEPTOR AFFINITY; SIDE EFFECT REDUCTION | ASTRAZENECA CANADA INC. (CA) | 2002-12-24 | — | — | US | disclosed |