Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | POLA1 | P09884 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.43 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11291604 | 0.98 | DRD2 (0.49) | DRD2DRD3KDM1AOPRM1OPRD1 | |
| SCHEMBL11297637 | 0.88 | KDM1A (0.54) | DRD2DRD3KDM1AOPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL11296787 | 0.86 | KDM1A (0.52) | DRD2DRD3KDM1AOPRM1OPRK1 | |
| SCHEMBL8768777 | 0.85 | DRD2 (0.54) | DRD2DRD3KDM1AOPRM1OPRK1 | |
| SCHEMBL8767448 | 0.85 | DRD2 (0.54) | DRD2DRD3KDM1AOPRM1OPRK1 | |
| SCHEMBL11350059 | 0.81 | GRIN2D (0.43) | OPRM1OPRD1OPRK1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL11296513 | 0.80 | OPRM1 (0.43) | DRD2DRD3KDM1AOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL11305258 | 0.80 | GRIN2D (0.43) | OPRM1OPRD1OPRK1ALDH1A1CYP3A4 | |
| SCHEMBL7670096 | 0.80 | OPRM1 (0.66) | DRD2DRD3KDM1AOPRM1OPRD1 | |
| SCHEMBL7661867 | 0.80 | OPRM1 (0.66) | DRD2DRD3KDM1AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005821-B1 | INDANAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1982-12-08 | — | — | EP | disclosed |
| EP-0005821-A1 | Indanamine derivatives, process for their preparation and medicaments containing them | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1979-12-12 | — | — | EP | disclosed |