Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 6/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.33 |
| ▸ | RASGRP3 | Q8IV61 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RASGRP1 | O95267 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12059177 | 0.80 | PRKCA (0.39) | PRKCAPRKCERASGRP3PRKCDSMN1; SMN2 | |
| SCHEMBL7070815 | 0.78 | PRKCA (0.37) | PRKCAPRKCERASGRP3PRKCD | |
| SCHEMBL4953813 | 0.75 | PRKCA (0.38) | PRKCAPRKCERASGRP3GAAPRKCD | |
| SCHEMBL4953817 | 0.75 | PRKCA (0.38) | PRKCAPRKCEPRKCDSMN1; SMN2 | |
| SCHEMBL6548888 | 0.69 | ADRA2A (0.35) | ALDH1A1KDM4EMAPTMAOBADORA2A | |
| SCHEMBL13811590 | 0.69 | ALDH1A1 (0.55) | ALDH1A1KDM4EGLAMAPTMAOB | |
| SCHEMBL4954525 | 0.66 | PRKCA (0.40) | PRKCAPRKCERASGRP3GAAPRKCD | |
| SCHEMBL4954531 | 0.66 | PRKCA (0.40) | PRKCAPRKCEPRKCDSMN1; SMN2 | |
| SCHEMBL4952252 | 0.66 | SMN1; SMN2 (0.38) | PRKCAPRKCESMN1; SMN2 | |
| SCHEMBL4952249 | 0.66 | SMN1; SMN2 (0.38) | PRKCAPRKCERASGRP3GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479608-B1 | Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-11-12 | — | — | US | disclosed |