SCHEMBL7070815

SCHEMBL7070815

CCC1(CC)C(=O)OCC(C)(COC(=O)C(C)(C)C)N1OC(C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 11/20 0.37
PRKCE Q02156 3/20 0.34
RASGRP3 Q8IV61 2/20 0.34
PRKCD Q05655 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7070697 0.89 TSHR (0.34) PRKCAPRKCERASGRP3PRKCD
SCHEMBL12059177 0.80 PRKCA (0.39) PRKCAPRKCERASGRP3PRKCD
SCHEMBL5385910 0.80 IDH1 (0.34)
SCHEMBL7070705 0.79 HSD11B1 (0.32)
SCHEMBL7670571 0.78 ALDH1A1 (0.34) PRKCAPRKCERASGRP3PRKCD
SCHEMBL4953813 0.75 PRKCA (0.38) PRKCAPRKCERASGRP3PRKCD
SCHEMBL4953817 0.75 PRKCA (0.38) PRKCAPRKCEPRKCD
SCHEMBL5389794 0.73 IDH1 (0.33)
SCHEMBL7070371 0.71 IDH1 (0.34)
SCHEMBL7070810 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664353-B2 Compounds providing stable free radical-mediated polymerization processes which yield polymers having low polydispersity at enhanced rates of polymerization and enhanced monomer to polymer conversions CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-16 US disclosed
US-20030125494-A1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes NESVADBA PETER (CH) 2003-07-03 US disclosed
US-6479608-B1 Heterocyclic alkoxyamines as regulators in controlled radical polymerization processes CIBA SPECIALTY CHEMICALS CORPORATION 2002-11-12 US disclosed