Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665205 | 0.89 | F2 (0.58) | F2TMPRSS6 | |
| SCHEMBL7669520 | 0.89 | F2 (0.58) | F2TMPRSS6 | |
| SCHEMBL7674656 | 0.86 | F2 (0.53) | F2TMPRSS6 | |
| SCHEMBL7667753 | 0.82 | F2 (0.52) | F2TMPRSS6 | |
| SCHEMBL7673733 | 0.80 | MAPT (0.49) | F2TMPRSS6 | |
| SCHEMBL7676248 | 0.79 | F2 (0.57) | F2TMPRSS6 | |
| SCHEMBL7690859 | 0.79 | MEP1B (0.62) | F2TMPRSS6 | |
| SCHEMBL7675632 | 0.78 | SMN1; SMN2 (0.51) | F2TMPRSS6 | |
| Acetic Acid SCHEMBL7667840 | 0.77 | TMPRSS6 (0.55) | F2TMPRSS6 | |
| Acetic Acid SCHEMBL7663094 | 0.77 | TMPRSS6 (0.55) | F2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403644-B1 | FOR PREVENTION AND/OR TREATMENT OF DISEASES INDUCED BY OVEREXPRESSION AND EXCESS ACTIVITY OF MATRIX METALLOPROTEINASE; FOR EXAMPLE, RHEUMATOID, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| US-6177466-B1 | Sulfonylamino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-0757037-A2 | Sulfonylamino acid derivatives as metalloproteinase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-05 | — | — | EP | disclosed |