Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | KDM4B | O94953 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | GCK | P35557 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672845 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL7000771 | 0.76 | KDM4A (0.45) | ALDH1A1SMN1; SMN2KDM4AKDM4BKDM5C | |
| SCHEMBL7001335 | 0.76 | BCAT2 (0.52) | ALDH1A1GCKMEN1KMT2ANPC1 | |
| SCHEMBL6154660 | 0.74 | SMN1; SMN2 (0.75) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL29503163 | 0.72 | GAA (0.55) | ALDH1A1SMN1; SMN2GAAPOLBHSD17B10 | |
| SCHEMBL1397448 | 0.72 | GAA (0.55) | ALDH1A1SMN1; SMN2GAAPOLBHSD17B10 | |
| SCHEMBL7002815 | 0.71 | POLB (0.55) | ALDH1A1MEN1KMT2APOLBRAB9A | |
| SCHEMBL7676444 | 0.71 | FLT3 (0.55) | ALDH1A1MEN1KMT2ANPSR1NPC1 | |
| SCHEMBL29646375 | 0.71 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4AKDM4BKDM5C | |
| SCHEMBL14482756 | 0.71 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2KDM4AKDM4BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |