Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7000771 | 0.88 | KDM4A (0.45) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7672533 | 0.85 | ALDH1A1 (0.56) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7001335 | 0.78 | BCAT2 (0.52) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL1930005 | 0.74 | EPHB4 (0.40) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL16246364 | 0.73 | PTK2 (0.49) | ALDH1A1RAB9AMEN1KMT2AFLT3 | |
| SCHEMBL20838914 | 0.72 | ADORA1 (0.58) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL27255187 | 0.72 | KMT2A (0.55) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9522605 | 0.72 | ADORA3 (0.57) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL7676444 | 0.72 | FLT3 (0.55) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL12314189 | 0.72 | MEN1 (0.76) | RAB9AMEN1KMT2ANPC1GRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |