Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.69 |
| ▸ | EP300 | Q09472 | 1/20 | 0.69 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | METAP2 | P50579 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678353 | 0.90 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 (0.62) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300PRMT1NPC1GAA | |
| SCHEMBL21275460 | 0.88 | RAB9A (0.76) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300PRMT1NPC1GAA | |
| SCHEMBL331600 | 0.87 | NPC1 (0.69) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300PRMT1NPC1GAA | |
| SCHEMBL12368193 | 0.84 | MEN1 (0.66) | NPC1GAALMNATP53HTT | |
| SCHEMBL9281809 | 0.83 | GFER (0.76) | NPC1GAALMNAMAPTGFER | |
| SCHEMBL14413353 | 0.82 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 (1.00) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300PRMT1NPC1GAA | |
| SCHEMBL845142 | 0.82 | LMNA (1.00) | NPC1GAALMNATP53HTT | |
| SCHEMBL21446829 | 0.82 | KDM4E (0.72) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300PRMT1NPC1GAA | |
| SCHEMBL3182095 | 0.82 | ALDH1A1 (0.67) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300PRMT1NPC1GAA | |
| SCHEMBL27491350 | 0.82 | CYP1A2 (0.70) | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16EP300PRMT1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151720-A1 | NAPHTHOL DERIVATIVES | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2002-10-17 | — | — | US | disclosed |
| EP-0421293-B1 | Aqueous preparations of C.I. azoic diazo components their manufacture and their use | HOECHST AG (DE) | 1996-08-28 | — | — | EP | disclosed |
| EP-0372536-B1 | ONE-PHASE PROCESS FOR PRODUCING PRINTS USING REACTIVE DYES BESIDES AZOIC DEVELOPING DYES ON ALKALI-PRE-IMPREGNATED TEXTILES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-5104416-A | Textile printing pastes; simplified preparation | HOECHT AKTIENGESELLSCHAFT (DE) | 1992-04-14 | — | — | US | disclosed |
| EP-0421293-A2 | Aqueous preparations of C.I. azoic diazo components their manufacture and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0372536-A2 | One-phase process for producing prints using reactive dyes besides azoic developing dyes on alkali-pre-impregnated textiles | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151720-A1 | NAPHTHOL DERIVATIVES | NAP1L1, IK, NAP1L4 | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 1294/4885EP300 2079/4885PRMT1 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.