Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL3862996 | 0.82 | LMNA (0.57) | LMNAL3MBTL1SIGMAR1NPC1 | |
| Tannin Pyrogallol SCHEMBL22288201 | 0.80 | LMNA (0.55) | LMNAL3MBTL1TAAR1NPC1 | |
| Biphenyl SCHEMBL8087383 | 0.80 | LMNA (0.55) | LMNAL3MBTL1SIGMAR1NPC1 | |
| Bromobenzene SCHEMBL2045059 | 0.78 | LMNA (0.52) | LMNAL3MBTL1LTA4HSIGMAR1SLC6A2 | |
| Benzenethiol SCHEMBL4312885 | 0.78 | LMNA (0.52) | LMNAL3MBTL1LTA4HMAOATP53 | |
| Chlorobenzene SCHEMBL108740 | 0.78 | LMNA (0.52) | LMNAL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| Phenol SCHEMBL3315051 | 0.78 | LMNA (0.52) | LMNAL3MBTL1LTA4HPIN1POLB | |
| SCHEMBL449609 | 0.78 | LMNA (0.52) | LMNAL3MBTL1MAOAMAOBTP53 | |
| O-Xylene SCHEMBL28066372 | 0.77 | LMNA (0.57) | LMNAL3MBTL1MAOAMAOBSLC6A4 | |
| Biphenyl SCHEMBL10925385 | 0.77 | LMNA (0.50) | LMNAL3MBTL1SIGMAR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399786-B1 | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |
| US-20020045598-A1 | Nonacyclic nodulisporic acid derivatives | MERCK SHARP & DOHME CORP. | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045598-A1 | Nonacyclic nodulisporic acid derivatives | CYP51A1, NOD1, FDPS | LMNA 4308/4885L3MBTL1 4617/4885LTA4H 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.