Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671780 | 0.82 | TUBB4A (0.45) | CYP19A1KDM4ECALM1AOC3DAO | |
| SCHEMBL7690876 | 0.80 | CYP1A2 (0.51) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL31428 | 0.79 | CA2 (0.71) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL31275634 | 0.79 | CA2 (0.71) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL1776797 | 0.77 | TRPA1 (0.34) | CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL266403 | 0.77 | CA2 (0.68) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| Water SCHEMBL8587595 | 0.77 | CA2 (0.68) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL16641094 | 0.77 | CYP19A1 (0.77) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL31157848 | 0.77 | CYP19A1 (0.77) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL7668663 | 0.76 | TAAR1 (0.38) | CYP1A2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395730-B1 | CARDIOVASCULAR DISORDERS | ICAGEN, INC. | 2002-05-28 | — | — | US | disclosed |
| US-6174908-B1 | TREATING DISEASE, CONDITION, OR DISORDER WHICH RESPONDS TO INHIBITION OF POTASSIUM CHANNEL FUNCTION BY ADMINISTERING THIAZOLIDONE OR METATHIAZONONE COMPOUND, ITS SALT, AMIDE, ESTER, COMPLEX, CHELATE, HYDRATE, STEREOISOMER, METABOLITE | ICAGEN, INC. | 2001-01-16 | — | — | US | disclosed |