Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20231243 | 0.84 | TSHR (0.42) | TSHRALDH1A1IMPDH2IMPDH1NPC1 | |
| SCHEMBL28252982 | 0.83 | PTPN1 (0.36) | TSHRALDH1A1IMPDH2IMPDH1NPC1 | |
| SCHEMBL16952177 | 0.83 | ALDH1A1 (0.36) | TSHRALDH1A1NPC1RAB9AGAA | |
| SCHEMBL16953027 | 0.82 | MAPT (0.35) | TSHRALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL7717027 | 0.82 | TSHR (0.38) | TSHRALDH1A1IMPDH2IMPDH1NPC1 | |
| SCHEMBL7674083 | 0.82 | TSHR (0.41) | TSHRALDH1A1IMPDH2IMPDH1NPC1 | |
| SCHEMBL6736896 | 0.80 | POLB (0.47) | TSHRALDH1A1IMPDH2IMPDH1GAA | |
| SCHEMBL129790 | 0.80 | ALDH1A1 (0.46) | ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL16956180 | 0.78 | PDK2 (0.34) | TSHRALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL23286532 | 0.76 | IMPDH2 (0.38) | ALDH1A1IMPDH2IMPDH1HTR2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |