Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674563 | 1.00 | CRHBP (0.47) | CRHBPGFERCRHR2ALDH1A1KMT2A | |
| SCHEMBL8328132 | 0.79 | MGLL (0.41) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL6966482 | 0.78 | CYP1A2 (0.42) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL7232423 | 0.78 | MGLL (0.39) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL5663686 | 0.78 | MGLL (0.42) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL5661272 | 0.78 | MGLL (0.42) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL5661991 | 0.78 | MGLL (0.42) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL7564445 | 0.78 | MGLL (0.39) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL7226122 | 0.77 | MGLL (0.42) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL7225595 | 0.77 | MGLL (0.41) | ALDH1A1MGLLCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |