Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966482 | 0.90 | CYP1A2 (0.42) | MGLLCYP1A2CYP2D6FAAH | |
| SCHEMBL7962604 | 0.82 | CYP1A2 (0.41) | MGLLCYP1A2CYP2D6FAAH | |
| SCHEMBL5663686 | 0.81 | MGLL (0.42) | MGLLCYP1A2CYP2D6FAAH | |
| SCHEMBL5661272 | 0.81 | MGLL (0.42) | MGLLCYP1A2CYP2D6FAAH | |
| SCHEMBL5661991 | 0.81 | MGLL (0.42) | MGLLCYP1A2CYP2D6FAAH | |
| SCHEMBL7232423 | 0.79 | MGLL (0.39) | MGLLCYP1A2CYP2D6FAAH | |
| SCHEMBL7674563 | 0.79 | CRHBP (0.47) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL7564445 | 0.79 | MGLL (0.39) | MGLLCYP1A2CYP2D6FAAH | |
| SCHEMBL7674567 | 0.79 | CRHBP (0.47) | MGLLCYP1A2CYP2D6 | |
| SCHEMBL7226122 | 0.77 | MGLL (0.42) | MGLLCYP1A2CYP2D6FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866708-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0866708-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997017969-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |