Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA3 | P07451 | 2/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.65 |
| ▸ | CA6 | P23280 | 2/20 | 0.65 |
| ▸ | DPP4 | P27487 | 2/20 | 0.65 |
| ▸ | CA5A | P35218 | 2/20 | 0.65 |
| ▸ | CA7 | P43166 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TYR | P14679 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557028 | 1.00 | HCAR2 (0.65) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL14081549 | 0.88 | HCAR2 (0.81) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL68395 | 0.88 | HCAR2 (0.81) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL713717 | 0.88 | HCAR2 (0.81) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL11835203 | 0.85 | HCAR2 (0.77) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL18662489 | 0.85 | HCAR2 (0.77) | HCAR2CA12AKR1B10CA1CA2 | |
| Hydrochloric Acid SCHEMBL8378608 | 0.85 | HCAR2 (0.77) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL19824692 | 0.84 | F3 (0.64) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL4946176 | 0.81 | HCAR2 (0.71) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL4946181 | 0.81 | HCAR2 (0.71) | HCAR2CA12AKR1B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365830-B2 | Ligand-exchangeable janus nanoparticles and methods of making the same | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2025-07-22 | — | — | US | claimed |
| CN-119752439-A | Multistep circularly polarized light-emitting inversion solid cholesteric liquid crystal, preparation method and application thereof | 同济大学 | 2025-04-04 | — | — | CN | claimed |
| US-20220259490-A1 | LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME | Alliance for Energy Innovation, LLC | 2022-08-18 | — | — | US | claimed |
| WO-2020252075-A1 | LIGAND-EXCHANGEABLE JANUS NANOPARTICLES AND METHODS OF MAKING THE SAME | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2020-12-17 | — | — | WO | claimed |
| US-10544168-B2 | Ligand-exchangeable nanoparticles and methods of making the same | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2020-01-28 | — | — | US | claimed |
| EP-3208301-B1 | RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME | TOSOH CORP (JP) | 2019-04-03 | — | — | EP | claimed |
| US-20170362255-A1 | LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME | Alliance for Energy Innovation, LLC | 2017-12-21 | — | — | US | claimed |
| US-12365830-B2 | Ligand-exchangeable janus nanoparticles and methods of making the same | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2025-07-22 | — | — | US | disclosed |
| CN-119752439-A | Multistep circularly polarized light-emitting inversion solid cholesteric liquid crystal, preparation method and application thereof | 同济大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-117751113-A | Aromatic acetylene derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | UNIVERSITY OF DURHAM | 2023-12-05 | — | — | US | disclosed |
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-116891409-A | Photoactive compound, photoresist composition comprising the same, and pattern forming method | 罗门哈斯电子材料有限责任公司 | 2023-10-17 | — | — | CN | disclosed |
| US-20040248118-A1 | Method for producing l-amino acids | SHOWA DENKO K.K. (JP) | 2004-12-09 | — | — | US | disclosed |
| WO-2004046096-A2 | NOVEL LIGANDS THAT ARE ANTAGONISTS OF RAF RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT,S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |
| EP-1399577-A1 | METHOD FOR PRODUCING L-AMINO ACIDS | Showa Denko K.K. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6683090-B1 | N-(1-AZABICYCLO(2.2.2)OCT-3-YL)PROPENAMIDE DERIVATIVES; PSYCHOTIC AND INTELLECTUAL IMPAIRMENT DISORDERS | ASTRAZENECA AB (SE) | 2004-01-27 | — | — | US | disclosed |
| WO-2003000915-A1 | METHOD FOR PRODUCING L-AMINO ACIDS | SHOWA DENKO K.K. (JP) | 2003-01-03 | — | — | WO | disclosed |
| EP-1233964-A1 | NEW USE AND NOVEL N-AZABICYCLO-AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001036417-A1 | NEW USE AND NOVEL N-AZABICYCLO-AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544168-B2 | Ligand-exchangeable nanoparticles and methods of making the same | CA6, CA13, EPCAM | HCAR2 11/4885CA12 6/4885AKR1B10 1196/4885 |
| US-11833203-B2 | Synthetic retinoids (in cell modulation) | RARA, RARB, RXRA | HCAR2 132/4885CA12 3772/4885AKR1B10 385/4885 |
| US-20170362255-A1 | LIGAND-EXCHANGEABLE NANOPARTICLES AND METHODS OF MAKING THE SAME | CA6, CA13, EPCAM | HCAR2 11/4885CA12 6/4885AKR1B10 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.