Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ECE1 | P42892 | 5/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563351 | 0.85 | MMP9 (0.56) | MMP9MMP8FFAR1GPR84MEN1 | |
| SCHEMBL7671952 | 0.81 | MMP9 (0.47) | MMP9MMP8FFAR1GPR84MEN1 | |
| SCHEMBL7669468 | 0.81 | MMP9 (0.58) | MMP9MMP8MEN1KMT2AECE1 | |
| SCHEMBL7677146 | 0.78 | MAPT (0.44) | MMP9MMP8FFAR1GPR84MEN1 | |
| SCHEMBL7674900 | 0.77 | MEN1 (0.49) | MMP9MMP8MEN1KMT2ARAB9A | |
| SCHEMBL7676896 | 0.77 | MAPT (0.63) | MEN1KMT2AGAA | |
| SCHEMBL7674972 | 0.77 | TRPV1 (0.52) | ECE1GAA | |
| SCHEMBL4001238 | 0.76 | GPR84 (0.54) | MMP9MMP8FFAR1GPR84MEN1 | |
| SCHEMBL27421440 | 0.74 | GPR84 (0.53) | FFAR1GPR84MEN1KMT2ASTING1 | |
| SCHEMBL27514167 | 0.72 | GPR84 (0.61) | FFAR1GPR84MEN1KMT2ANOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |