Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563351 | 0.90 | MMP9 (0.56) | MMP9MMP8MEN1KMT2AGAA | |
| SCHEMBL7674900 | 0.81 | MEN1 (0.49) | MMP9MMP8MEN1KMT2AGAA | |
| SCHEMBL7676891 | 0.81 | MMP9 (0.43) | MMP9MMP8MEN1KMT2AGAA | |
| SCHEMBL7674972 | 0.79 | TRPV1 (0.52) | GAAECE1 | |
| SCHEMBL4001238 | 0.77 | GPR84 (0.54) | MMP9MMP8MEN1KMT2AGAA | |
| SCHEMBL7677146 | 0.77 | MAPT (0.44) | MMP9MMP8MEN1KMT2AGAA | |
| SCHEMBL27421440 | 0.76 | GPR84 (0.53) | MEN1KMT2AGAAFFAR1GPR84 | |
| SCHEMBL7856260 | 0.76 | MMP9 (0.52) | MMP9MMP8MEN1KMT2AGAA | |
| SCHEMBL7671960 | 0.75 | MAPT (0.64) | MMP9MMP8MEN1KMT2AGAA | |
| SCHEMBL8488110 | 0.75 | MEN1 (0.58) | MMP9MMP8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |