Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677881 | 0.79 | HTR1A (0.57) | SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7674904 | 0.77 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1PKMPKLR | |
| SCHEMBL7677363 | 0.75 | NPSR1 (0.54) | MAPTSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL7678792 | 0.74 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL31744700 | 0.71 | PKM (0.75) | MAPTSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL7671809 | 0.71 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11149263 | 0.71 | ALDH1A1 (0.50) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL7650108 | 0.70 | MEN1 (0.49) | MAPTSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL7676036 | 0.70 | MEN1 (0.51) | MAPTSMN1; SMN2ALDH1A1KDM4EPKM | |
| SCHEMBL4666381 | 0.70 | ALDH1A1 (0.56) | MAPTSMN1; SMN2ALDH1A1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |