Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675265 | 0.84 | LTA4H (0.50) | ABCB1MAOBMEN1KMT2AFFAR1 | |
| SCHEMBL4599932 | 0.77 | BCHE (0.53) | BCHEMAOBMEN1KMT2A | |
| SCHEMBL7670255 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL28253242 | 0.76 | ALOX5 (0.49) | BCHEMAOBMEN1KMT2AL3MBTL1 | |
| SCHEMBL3948493 | 0.76 | MAOB (0.58) | BCHEMAOBALOX5 | |
| SCHEMBL7669645 | 0.76 | MAOB (0.44) | MAOBL3MBTL1RAB9A | |
| SCHEMBL27618450 | 0.76 | MAOB (0.51) | BCHEMAOBL3MBTL1RAB9AALOX5 | |
| SCHEMBL920022 | 0.75 | MAOB (0.53) | MAOBTDP1NPC1RAB9A | |
| SCHEMBL7669559 | 0.75 | MAOB (0.45) | MAOBMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL7671780 | 0.75 | TUBB4A (0.45) | MAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395730-B1 | CARDIOVASCULAR DISORDERS | ICAGEN, INC. | 2002-05-28 | — | — | US | disclosed |
| US-6174908-B1 | TREATING DISEASE, CONDITION, OR DISORDER WHICH RESPONDS TO INHIBITION OF POTASSIUM CHANNEL FUNCTION BY ADMINISTERING THIAZOLIDONE OR METATHIAZONONE COMPOUND, ITS SALT, AMIDE, ESTER, COMPLEX, CHELATE, HYDRATE, STEREOISOMER, METABOLITE | ICAGEN, INC. | 2001-01-16 | — | — | US | disclosed |