Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.41 |
| ▸ | MMP9 | P14780 | 8/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BMP1 | P13497 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888752 | 0.94 | MMP2 (0.44) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL4654917 | 0.87 | MMP2 (0.56) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6073739 | 0.82 | MMP2 (0.61) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7676093 | 0.81 | SMN1; SMN2 (0.34) | SYKL3MBTL1BMP1BCHECNR2 | |
| SCHEMBL14289008 | 0.80 | MMP2 (0.57) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL6889607 | 0.75 | SMN1; SMN2 (0.35) | BCHECNR2 | |
| SCHEMBL14271455 | 0.74 | MMP2 (0.40) | MMP2MMP9MMP1MMP13ALDH1A1 | |
| SCHEMBL5139951 | 0.74 | MMP2 (0.62) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL4958777 | 0.74 | MMP2 (0.62) | MMP2MMP9MMP1MMP3MMP7 | |
| SCHEMBL7400840 | 0.73 | SYK (0.46) | MMP2MMP9ALDH1A1SYKBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020041878-A1 | Vitronectin receptor antagonist pharmaceuticals | LANTHEUS MEDICAL IMAGING, INC. | 2002-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020041878-A1 | Vitronectin receptor antagonist pharmaceuticals | ADGRF1, RXFP1, VCAM1 | MMP2 2243/4885MMP9 2451/4885MMP1 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.