SCHEMBL767599

SCHEMBL767599

CCO[Si](CCCOC(=O)CCC(=O)O[SiH3])(OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.37
DGKA P23743 1/20 0.37
ADRA2A P08913 1/20 0.35
ADRA1A P35348 1/20 0.35
MAPT P10636 1/20 0.34
BLM P54132 1/20 0.34
NAAA Q02083 1/20 0.33
CYP1A2 P05177 1/20 0.33
DNM1 Q05193 1/20 0.32
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
EPHX2 P34913 7/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL176417 0.92 DGKA (0.42) HTR2CDGKAADRA2AADRA1AMAPT
SCHEMBL176416 0.85 HTR2C (0.38) HTR2CDGKAADRA2AADRA1AMAPT
SCHEMBL29028494 0.85 HTR2C (0.47) HTR2CDGKAADRA2AADRA1AMAPT
SCHEMBL6267406 0.85 DGKA (0.44) HTR2CDGKAADRA2AADRA1AMAPT
SCHEMBL28289669 0.85 HTR2C (0.47) HTR2CDGKAADRA2AADRA1AMAPT
SCHEMBL8839165 0.83 DGKA (0.52) HTR2CDGKAMAPTNAAACYP1A2
SCHEMBL12080684 0.82 DGKA (0.38) HTR2CDGKAADRA2AADRA1AMAPT
SCHEMBL1224968 0.81 NAAA (0.52) HTR2CDGKANAAADNM1GAA
SCHEMBL9323713 0.81 GAA (0.46) DGKAMAPTNAAAGAA
SCHEMBL28289681 0.81 ADRA2A (0.43) HTR2CDGKAADRA2AADRA1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9511392-B2 Method for coating metal surfaces in a multi-step method CHEMETALL GMBH (DE) 2016-12-06 US disclosed
US-9364855-B2 Method for coating metal surfaces with an activating agent prior to phosphating CHEMETALL GMBH (DE) 2016-06-14 US disclosed
US-9358574-B2 Method for coating metal surfaces with an activating agent prior to phosphating CHEMETALL GMBH (DE) 2016-06-07 US disclosed
US-20140051311-A1 METHOD FOR COATING METAL SURFACES WITH AN ACTIVATING AGENT PRIOR TO PHOSPHATING CHEMETALL GMBH (DE) 2014-02-20 US disclosed
US-20120070674-A1 METHOD FOR COATING METAL SURFACES IN A MULTI-STEP METHOD CHEMETALL GMBH (DE) 2012-03-22 US disclosed
US-20110226159-A1 METHOD FOR COATING METAL SURFACES WITH AN ACTIVATING AGENT PRIOR TO PHOSPHATING CHEMETALL GMBH (DE) 2011-09-22 US disclosed