Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280287 | 0.81 | — | — | |
| SCHEMBL7676034 | 0.78 | MEN1 (0.39) | PIM1NTRK1CDC7GAAMEN1 | |
| SCHEMBL2280290 | 0.74 | PARP1 (0.42) | MAP2K1CLK4DYRK1BPLK4CHEK1 | |
| SCHEMBL30949148 | 0.73 | LRRK2 (0.45) | PIM1NTRK1CDC7GAAMEN1 | |
| SCHEMBL29263048 | 0.73 | LRRK2 (0.45) | PIM1NTRK1CDC7GAAMEN1 | |
| SCHEMBL7680894 | 0.71 | BCAT2 (0.50) | BCAT2MEN1KMT2AIKBKB | |
| SCHEMBL5335642 | 0.70 | CHEK2 (0.40) | PIM1NTRK1CDC7BCAT2FYN | |
| SCHEMBL14917462 | 0.70 | MKNK1 (0.49) | PIM1NTRK1CDC7GAABCAT2 | |
| SCHEMBL23199045 | 0.68 | NTRK1 (0.52) | PIM1NTRK1CDC7GAABCAT2 | |
| SCHEMBL28143127 | 0.68 | CDC7 (0.46) | PIM1NTRK1CDC7GAABCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369088-B2 | ANTIDIABETIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |