Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 5/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 4/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2280287 | 0.81 | — | — | |
| SCHEMBL27514880 | 0.71 | MEN1 (0.46) | MEN1GAAKMT2APOLBNTRK1 | |
| SCHEMBL18210515 | 0.71 | MYC (0.36) | PIM1KDM4EALDH1A1ADORA2A | |
| SCHEMBL7680902 | 0.71 | BCAT2 (0.40) | — | |
| SCHEMBL5335642 | 0.70 | CHEK2 (0.40) | NTRK1PIM1CDC7KDRALDH1A1 | |
| SCHEMBL14917460 | 0.70 | MEN1 (0.47) | MEN1GAAKMT2APOLBNTRK1 | |
| SCHEMBL27907482 | 0.68 | MEN1 (0.54) | MEN1GAAKMT2APOLBNTRK1 | |
| SCHEMBL22396471 | 0.67 | MYC (0.50) | GAAKMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL1533663 | 0.66 | MEN1 (0.48) | MEN1GAAKMT2APOLBNTRK1 | |
| SCHEMBL3806342 | 0.66 | NR1H2 (0.36) | GAAPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369088-B2 | ANTIDIABETIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |