Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.40 |
| ▸ | ABAT | P80404 | 3/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073812 | 0.87 | ALDH5A1 (0.50) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL7074379 | 0.83 | KDM4E (0.50) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL13257341 | 0.82 | KDM4E (0.61) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL7074332 | 0.80 | ALDH1A1 (0.51) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL7681882 | 0.78 | ALDH1A1 (0.46) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL17557781 | 0.77 | CYP2A6 (0.47) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL7074382 | 0.76 | KDM4E (0.42) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL19923199 | 0.75 | KDM4E (0.57) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL10106351 | 0.75 | ALDH1A1 (0.51) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL18714281 | 0.75 | KDM4E (0.61) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495580-B1 | A BENZYLIDENE DERIVATIVE CONTAINING HETEROCYCLIC RING IS USEFUL AS PNEUMOVIRUS INHIBITOR | VIROPHARMA INCORPORATED | 2002-12-17 | — | — | US | disclosed |