Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.42 |
| ▸ | ABAT | P80404 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | UNG | P13051 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073812 | 0.88 | ALDH5A1 (0.50) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL7074379 | 0.82 | KDM4E (0.50) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL10106351 | 0.79 | ALDH1A1 (0.51) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL10106319 | 0.78 | ALDH1A1 (0.45) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL10106344 | 0.78 | RAB9A (0.43) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL10106334 | 0.78 | KDM4E (0.43) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL13257341 | 0.78 | KDM4E (0.61) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL10119404 | 0.77 | PTGS2 (0.39) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL7676281 | 0.76 | KDM4E (0.47) | KDM4EPTGS2RAB9AALDH5A1ABAT | |
| SCHEMBL10106338 | 0.75 | ALDH1A1 (0.48) | KDM4EPTGS2RAB9AALDH5A1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | NITZ THEODORE J (US) | 2003-05-15 | — | — | US | disclosed |
| US-6495580-B1 | A BENZYLIDENE DERIVATIVE CONTAINING HETEROCYCLIC RING IS USEFUL AS PNEUMOVIRUS INHIBITOR | VIROPHARMA INCORPORATED | 2002-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092685-A1 | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | TTPA, HAVCR2, PML | KDM4E 4428/4885PTGS2 935/4885RAB9A 2880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.