Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675273 | 0.88 | P2RX7 (0.39) | PTGER4HTR3AHTR4PDE4APDE4B | |
| SCHEMBL7678800 | 0.88 | ALDH1A1 (0.37) | PTGER4HTR3AHTR4PDE4APDE4B | |
| SCHEMBL7684703 | 0.88 | CNR1 (0.46) | HTR3AHTR4PDE4APDE4BPDE4C | |
| SCHEMBL678914 | 0.87 | P2RX7 (0.38) | HTR3AHTR4PDE4APDE4BPDE4C | |
| SCHEMBL7677391 | 0.85 | CNR1 (0.38) | HTR3AHTR4PDE4APDE4BPDE4C | |
| SCHEMBL7676323 | 0.85 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL7679461 | 0.82 | CNR1 (0.39) | PTGER4ACACBACACACNR1CNR2 | |
| SCHEMBL7677655 | 0.82 | CNR2 (0.40) | HTR3AHTR4PDE4APDE4BPDE4C | |
| SCHEMBL7684280 | 0.81 | CNR1 (0.43) | PAK1CNR1CNR2NPC1P2RX7 | |
| SCHEMBL12808578 | 0.80 | PAK1 (0.36) | HTR3AHTR4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |