Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675255 | 0.89 | CNR1 (0.40) | CNR2CNR1ACACBACACAMAPK14 | |
| SCHEMBL678914 | 0.86 | P2RX7 (0.38) | CNR2CNR1PDE4BPAK1PDE4A | |
| SCHEMBL7679361 | 0.86 | PDE4B (0.38) | PDE4BPDE4APDE4CPDE4DMAPK14 | |
| SCHEMBL7684703 | 0.85 | CNR1 (0.46) | CNR2CNR1PDE4BPAK1PDE4A | |
| SCHEMBL7677539 | 0.85 | HPGD (0.39) | CNR2PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7677645 | 0.84 | PTGS2 (0.40) | CNR2CNR1PDE4BPDE4APDE4C | |
| SCHEMBL7681363 | 0.84 | PTGS2 (0.41) | PDE4BPDE4APDE4CPDE4DNPC1 | |
| SCHEMBL7683343 | 0.84 | PDE4B (0.39) | PDE4BPDE4APDE4CPDE4DP2RX7 | |
| SCHEMBL12808578 | 0.83 | PAK1 (0.36) | CNR2CNR1PDE4BPAK1PDE4A | |
| SCHEMBL7676296 | 0.82 | PTGER4 (0.40) | CNR2CNR1PDE4BPAK1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |