Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.49 |
| ▸ | CES1 | P23141 | 4/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471753 | 0.85 | CES2 (0.49) | CES2CES1PARP1KEAP1KCNN4 | |
| SCHEMBL7466460 | 0.83 | CES2 (0.50) | CES2CES1PSEN1PSEN2APH1B | |
| SCHEMBL7474529 | 0.79 | DGAT1 (0.33) | CES2CES1 | |
| SCHEMBL6896203 | 0.77 | CES2 (0.45) | CES2CES1PSEN1PSEN2APH1B | |
| SCHEMBL7470109 | 0.77 | GAA (0.49) | CES2CES1KCNN4 | |
| SCHEMBL3736079 | 0.76 | CES2 (0.44) | CES2CES1PSEN1PSEN2APH1B | |
| SCHEMBL7682173 | 0.76 | CES2 (0.47) | CES2CES1CA9 | |
| SCHEMBL9311000 | 0.75 | CES2 (0.43) | CES2CES1PSEN1PSEN2APH1B | |
| SCHEMBL383806 | 0.73 | CES2 (0.46) | CES2CES1PSEN1PSEN2APH1B | |
| SCHEMBL11086841 | 0.73 | CES2 (0.47) | CES2CES1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |