Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.47 |
| ▸ | CES1 | P23141 | 4/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464767 | 0.82 | CES2 (0.49) | CES2CES1BCHEALDH1A1 | |
| SCHEMBL7676722 | 0.76 | CES2 (0.49) | CES2CES1CA9 | |
| SCHEMBL7471753 | 0.76 | CES2 (0.49) | CES2CES1DGAT1ALDH1A1 | |
| SCHEMBL3733998 | 0.75 | CES2 (0.42) | CES2CES1 | |
| SCHEMBL7470109 | 0.74 | GAA (0.49) | CES2CES1ALDH1A1GAA | |
| SCHEMBL14720840 | 0.74 | DGAT1 (0.53) | DGAT1ALDH1A1CA12CA1CA2 | |
| SCHEMBL7474529 | 0.72 | DGAT1 (0.33) | CES2CES1DGAT1CA1CA2 | |
| SCHEMBL7477905 | 0.70 | PDE2A (0.53) | CES2ALDH1A1GAA | |
| SCHEMBL4002335 | 0.70 | CES2 (0.42) | CES2CES1 | |
| SCHEMBL8013319 | 0.69 | CES2 (0.52) | CES2CES1BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |