Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 9/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27541050 | 0.90 | APLNR (0.41) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL27487153 | 0.89 | GLA (0.37) | APLNRALDH1A1MAPT | |
| SCHEMBL7678750 | 0.89 | APLNR (0.39) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL27502563 | 0.85 | APLNR (0.43) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL27410461 | 0.83 | ACHE (0.41) | APLNRHTTMAPK1ALDH1A1TSHR | |
| SCHEMBL27413423 | 0.81 | TLR8 (0.34) | MEN1KMT2APDE2APDE10A | |
| SCHEMBL7676400 | 0.79 | OXTR (0.41) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL6678132 | 0.79 | OXTR (0.41) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL27409634 | 0.78 | PDE10A (0.37) | APLNRHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL7682650 | 0.78 | APLNR (0.38) | APLNRHTTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103770-C | Quinoxalinediones | PFIZER RES AND DEV CO N V S A (IE) | 2003-03-26 | — | — | CN | disclosed |
| CN-1213369-A | Quinoxalinedione compound | PFIZER RES & DEV (IE) | 1999-04-07 | — | — | CN | disclosed |