Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678132 | 0.91 | OXTR (0.41) | APLNRHTTMEN1MAPK1KMT2A | |
| SCHEMBL7677420 | 0.89 | GLA (0.36) | APLNR | |
| SCHEMBL7682650 | 0.89 | APLNR (0.38) | APLNRHTTMEN1MAPK1KMT2A | |
| SCHEMBL27489462 | 0.89 | APLNR (0.41) | APLNRHTTMEN1MAPK1KMT2A | |
| SCHEMBL7681550 | 0.86 | APLNR (0.41) | APLNRHTTMEN1MAPK1KMT2A | |
| SCHEMBL7674184 | 0.85 | SLC2A1 (0.37) | APLNRHTTMEN1KMT2ATSHR | |
| SCHEMBL7676180 | 0.84 | ACHE (0.40) | APLNRHTTMEN1MAPK1KMT2A | |
| SCHEMBL7676400 | 0.83 | OXTR (0.41) | APLNRHTTMEN1MAPK1KMT2A | |
| SCHEMBL7677312 | 0.83 | OXTR (0.41) | APLNRHTTMEN1MAPK1KMT2A | |
| SCHEMBL7673869 | 0.82 | ALDH1A1 (0.43) | APLNRHTTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376490-B1 | STRONG N-METHYL-D-ASPARATE RECEPTOR ANTAGONISTS; USEFUL IN TREATING STROKES, ISCHEMIA, AND CENTRAL NERVOUS SYSTEM INJURIES | PFIZER INC | 2002-04-23 | — | — | US | disclosed |
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | disclosed |