Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 7/20 | 0.37 |
| ▸ | AKT2 | P31751 | 7/20 | 0.37 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679500 | 0.93 | CDK2 (0.43) | CDK2CDK4USP7AKT1AKT2 | |
| SCHEMBL7682045 | 0.91 | CDK2 (0.43) | CDK2MAPTCDK4USP7AKT1 | |
| SCHEMBL7674349 | 0.90 | TRPV1 (0.40) | CDK2CDK4USP7ADORA3 | |
| SCHEMBL7680034 | 0.90 | CDK2 (0.40) | CDK2MAPTCDK4USP7AKT1 | |
| SCHEMBL7680224 | 0.89 | ATM (0.42) | CDK2MAPTNPC1RAB9ACDK4 | |
| SCHEMBL7673988 | 0.89 | CHUK (0.43) | CDK2CDK4USP7 | |
| SCHEMBL7679621 | 0.88 | CDK2 (0.43) | CDK2MAPTKMT2ACDK4USP7 | |
| SCHEMBL7675092 | 0.88 | AKT1 (0.47) | CDK2MAPTNPC1RAB9ACDK4 | |
| SCHEMBL7673955 | 0.87 | NPC1 (0.42) | CDK2MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7680199 | 0.87 | TLR7 (0.39) | CDK2MAPTCDK4USP7AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |