Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673955 | 0.90 | NPC1 (0.42) | AKT1AKT2CDK2USP7MAPT | |
| SCHEMBL7679500 | 0.90 | CDK2 (0.43) | AKT1AKT2CDK2CDK4USP7 | |
| SCHEMBL7676480 | 0.90 | NAMPT (0.39) | CDK2IGF2BP2CDK4 | |
| SCHEMBL7675092 | 0.89 | AKT1 (0.47) | AKT1AKT2CDK2CDK4USP7 | |
| SCHEMBL7682045 | 0.88 | CDK2 (0.43) | AKT1AKT2CDK2CDK4USP7 | |
| SCHEMBL7677596 | 0.87 | CDK2 (0.41) | AKT1AKT2CDK2CDK4USP7 | |
| SCHEMBL7674349 | 0.87 | TRPV1 (0.40) | CDK2MCHR1CDK4USP7 | |
| SCHEMBL7680034 | 0.87 | CDK2 (0.40) | AKT1AKT2CDK2CDK4USP7 | |
| SCHEMBL7680009 | 0.86 | CDK2 (0.39) | AKT1AKT2CDK2CDK4USP7 | |
| SCHEMBL7676765 | 0.84 | POLB (0.46) | CDK2CDK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |