Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734902 | 0.79 | LMNA (0.35) | MAPTRAB9ALMNAMAPK1PTGS2 | |
| SCHEMBL31118436 | 0.75 | NPC1 (0.45) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL1223997 | 0.75 | NPC1 (0.45) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL6718195 | 0.75 | NPC1 (0.45) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL1098584 | 0.72 | NPC1 (0.47) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL1552822 | 0.71 | GAA (0.45) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL1224878 | 0.71 | NPC1 (0.67) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL1098582 | 0.71 | NPC1 (0.45) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL21614370 | 0.71 | NPC1 (0.45) | NPC1GAATAAR1PPOXMAPT | |
| SCHEMBL32675249 | 0.71 | NPC1 (0.45) | NPC1GAATAAR1PPOXMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420314-B1 | GRIGNARD ARYLATION OF A 3-FLUOROPYRIDINE; DESICCANTS, DEFOLIANTS; SELECTIVITY; ACTING AGAINST BROAD-LEAF AND GRASS WEEDS IN CROPS SUCH AS WHEAT, RICE, MAIZE, SOYA AND COTTON | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| US-6407245-B2 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | disclosed |
| US-20010012897-A1 | Substituted thiopyridines | HAMPRECHT GERHARD (DE) | 2001-08-09 | — | — | US | disclosed |
| US-6262273-B1 | REACTING A3-CHLORO-2-HALOPYRIDINE WITH THIO COMPOUND IN PRESENCE OF TRIFLUOROACETIC ACID OR PERCHLORIC ACID TO GIVE PYRIDINE THIOETHER COMPOUND WHICH IS OXIDIZED TO GIVE THIOPYRIDINE COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| US-6169184-B1 | REACTING SUBSTITUTED PYRIDINE WITH SPECIFIED ARYL COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-02 | — | — | US | disclosed |
| EP-0984933-A1 | SUBSTITUTED 2-PHENYL PYRIDINES, THEIR MANUFACTURE AND USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-15 | — | — | EP | disclosed |
| EP-0934275-A1 | SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-11 | — | — | EP | disclosed |
| EP-0931068-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998054137-A1 | SUBSTITUTED 2-PHENYL PYRIDINES, THEIR MANUFACTURE AND USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998011072-A1 | SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |
| WO-1998011069-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012897-A1 | Substituted thiopyridines | CBR1, CLIC1, CBR3 | NPC1 334/4885GAA 4757/4885TAAR1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.