Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.39 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042097 | 0.86 | FAAH (0.36) | CHRM4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7038329 | 0.83 | SMN1; SMN2 (0.53) | CHRM4HRH3KDM4EALDH1A1 | |
| SCHEMBL7036716 | 0.83 | SMN1; SMN2 (0.44) | CHRM4L3MBTL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7040117 | 0.80 | CYP3A4 (0.53) | HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7040587 | 0.79 | LSS (0.52) | HRH3ADRB2PTGIRKDM4EALDH1A1 | |
| SCHEMBL587589 | 0.72 | ALDH1A1 (0.62) | CHRM4L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7042155 | 0.71 | CXCR4 (0.54) | HRH3PTGIRKDM4EALDH1A1 | |
| SCHEMBL29524977 | 0.71 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1 | |
| SCHEMBL11239164 | 0.67 | SMN1; SMN2 (0.39) | CHRM4L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL11239169 | 0.67 | SMN1; SMN2 (0.39) | CHRM4L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339096-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERLIPIDAEMIAS, HYPERCHOLESTEROLAEMIAS AND ATHEROSCLEROSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-15 | — | — | US | disclosed |